Endocrine Abstracts

Background: Organ infiltration and metastasis are the only parameters defining malignancy of pancreatic endocrine tumors. Several studies had demonstrated the prognostic value of Ki-67 expression measured on histological sections obtained from the removed pancreatic endocrine tumors. We postulate that Ki-67 expression measured on fine needle aspiration cytology provides pre-operative indications of the malignancy of pancreatic endocrine tumors.Aim: Aims ...

Introduction: In latent autoimmune diabetes of adults (LADA), the progression to insulin-dependent diabetes is usually faster than in type 2 diabetes (T2DM) but the factors influencing this progression are not completely known. The aim of the present study was to determine whether GADA could be used as predictors of insulin dependence and whether GADA titre could define the risk of progression to insulin therapy in LADA patients. We looked for other biochemical and clinical pa...

Introduction: LADA is a heterogeneous population of diabetes subjects wherein subgroups can be identified based on their autoimmune status: the titre of autoantibodies to GAD.The aim of the study was to correlate, in LADA subjects, GADA titre, with the presence of other organ and non organ specific autoantibodies.Methods: LADA subjects (n=191) and type 2 diabetes (T2DM) subjects (n=382) were selected from the Non Insu...